Unconventional Motoring: An Overview of the Kin C and Kin I Kinesins

Kin I Kinesins Are Microtubule-Destabilizing Enzymes

Using in vitro assays with purified proteins, we show that XKCM1 and XKIF2, two distinct members of the internal catalytic domain (Kin I) kinesin subfamily, catalytically destabilize microtubules using a novel mechanism. Both XKCM1 and XKIF2 influence microtubule stability by targeting directly to microtubule ends where they induce a destabilizing conformational change. ATP hydrolysis recycles ...

2030’s Seniors : Kin and Step-Kin

Demographic computer microsimulation is applied to produce projections of numbers and distributions of close kin for the U.S. elderly of 2030. This paper reports results for the non-black population, with special emphasis on the numbers and possible roles of step-kin. The projections indicate that the elderly of 2030 are likely to be moderately deprived in terms of numbers of close living biolo...

Kin-Selection: The Rise and Fall of Kin-Cheaters

We demonstrate the existence of altruism via kin selection in artificial life and explore its nuances. We do so in the Avida system through a setup that is based on the behavior of colicinogenic bacteria: Organisms can kill unrelated organisms in a given radius but must kill themselves to do so. Initially, we confirm results found in the bacterial world: Digital organisms do sacrifice themselve...

Kin adopting kin: In the best interest of the children?

Kin Selection